Research studies

Key studies linking sleep and napping with productivity, health and safety

Key Productivity Studies

Sleep Deficit: The Performance Killer, C.A. Czeisler, B. Frye, Harvard Business Review, 22nd October 2006

Dr Charles Czeisler, Professor of Sleep Medicine at Harvard Medical School, points out that a week of sleeoing four or five hours a night impairs performance to the same extent as legal drunkenness. “We know that 24 hours without sleep or a week of sleeping four or five hours a night induces an impairment equivalent to a blood alcohol level of .1%. We would never say ‘This person is a great worker! He’s drunk all the time!’ yet we continue to celebrate people who sacrifice sleep.”
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The Restorative Effect of Naps on Perceptual Deterioration, Mednick, S., Nakayama, K., et. al., Nature Neuroscience, published online 28th May 2002,


“Here, we tested human subjects four times in one day and found that with repeated, within-day testing, perceptual thresholds actually increased progressively across the four test sessions. This performance deterioration was prevented either by shifting the target stimuli to an untrained region of visual space or by having the subjects take a mid-day nap between the second and third sessions.”
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Key Health Studies

The Association Between Sleep Duration and Weight Gain in Adults. A 6-year Prospective Study from the Quebec Family Study, J-P. Chaput, J-P. Despres, C. Bouchard, A. Tremblay, Sleep, Vol. 31, No. 4, 2008

In this study of 276 adults between the ages of 21 and 64 over the course of six years the study split subjects into three groups: short sleepers (5 to 6 hours), average sleepers (7 to 8 hours) and long sleepers (9 to 10 hours). They found that over the six years short sleepers were 35% more likely to experience a weight gain of 5 kgs and that short sleepers were 27% more likely to develop obesity.
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Siesta in Health Adults and Coronary Mortality in the Gerneral Population, A. Naska, E. Oikonomou, A. Trichopoulou, T. Psaltopoulou, D. Trichopoulou, Arch Intern Med, Vol. 167, 12th February 2007

In this collaboration between the University of Athens Medical School, Hellenic Health Foundation and Harvard School of Public Health researchers found that after eliminating other health factors, such as diet, exercise and smoking, those who took a regular mid-day nap were 37% less likely to die of heart disease. This rose to 64% in working men.
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Key Safety Studies

Behavioral and Physiological Consequences of Sleep Restriction, S. Banks and D. Dinges, Journal of Clinical Sleep Medicine, Vol. 3, No.5, 2007

In this study of healthy adults individuals were split into groups who were allowed either 4 hours of night time sleep, 6 hours or 8 hours. When tested after 14 days of sleep restriction those in the 4 hours sleep group were 14 times more likely to make an error in testing versus their baseline performance when well rested. The six hour group made 11 times more errors versus baseline, whilst the 8 hours group performed consistently well, despite some decrement.
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Alertness Management: Strategic Naps in Operational Settings, M. Rosekind et al, J. Sleep Research Society, 4, 62-66


Rosekind et al examined the beneficial effects of a brief nap in a group of airline pilots. The group was split into two groups – a rest group who were allowed a brief in-flight nap and a non-rest group who were required to maintain their usual in-flight activities. The Rest Group maintained consistent performance night and day, at the end of flights, and after multiple flight legs. The Rest Group demonstrated vigilance performance improvements from 16% in median reaction time to 34% in lapses compared to the No-Rest Group.
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Other Studies highlighting the benefits of a controlled rest
1. Naps as integral parts of the wake time within the human sleep-wake cycle.

ASCHOFF J.
J Biol Rhythms 1994;9(2):145-55.
Max-Planck-Institut fur Verhaltensphysiologie, Andechs, Germany.


Protocol: Thirteen subjects lived singly in an isolation unit without temporal cues for an average time span of 32 days. They signaled the times when they woke up, took a meal, and retired, noting in their diaries what kind of sleep (nap or main sleep) they were going to have.

Results: In five subjects the free-running circadian rhythms remained internally synchronized. The other eight subjects became internally desynchronized, with different periods in the sleep-wake cycle and in the rhythm of body temperature, or developed a “circa-bi-dian” rhythmicity (i.e., a state of the circadian system in which the temperature rhythm regains synchrony with the sleep-wake cycle in a 2:1 ratio). The duration of naps was positively correlated with the duration of wake time (after subtraction of the nap), as well as with the duration of wakefulness preceding the nap. In contrast, the duration of main sleep was negatively correlated with the preceding wake time.

Conclusions: It is concluded that naps are integral parts of the wake time, and that they follow the rules known from intermeal intervals and the perception of long time intervals such as 1 hr.

2. The effects of a 20 min nap in the mid-afternoon on mood, performance and EEG activity.
HAYASHI M, WATANABE M, HORI T.
Clin Neurophysiol 1999;110(2):272-9.
Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-hiroshima, Japan


Objective: The aim of the study is to examine the effects of a 20 min nap in the mid-afternoon on mood, performance and EEG activities.

Methods: Seven young adults who had normal sleep-wake habits without habitual daytime napping participated in the study. They underwent Nap and No-nap conditions at intervals of 1 week. After a nocturnal sleep recording (00:00-08:00 h), their EEG recordings during relaxed wakefulness, and their mood, performance and self-ratings of performance level were measured every 20 min from 10:00 to 18:00 h. For the nap condition, they went to bed at 14:00 h and were awakened when 20 min had elapsed from the onset of sleep stage 1. For the No-nap condition, they took a rest without sleep by sitting on a semi-reclining chair

Results: All of the subjects were awakened from sleep stage 2 during the nap. The 20 min nap improved the subjective sleepiness, performance level and self-confidence of their task performance. The nap also suppressed EEG alpha activity during eyes-open wakefulness.

Conclusions: The results suggest that a short 20 min nap in the mid-afternoon had positive effects upon the maintenance of the daytime vigilance level.
3. The effects of a short daytime nap after restricted night sleep.
GILLBERG M, KECKLUND G, AXELSSON J, AKERSTEDT T.
Sleep 1996;19(7):570-5.
Karolinska Institute, Stockholm, Sweden


Study: Eight subjects participated on three occasions in a study investigating the effect of a 30 minute daytime nap opportunity on alertness/sleepiness.

Protocols: The baseline condition was a normal home sleep (7.5 hours, with bedtime at 2300 hours). Sleep during the other two conditions was between 2400 hours and 0400 hours. During one of the two 4-hour conditions, a short nap was allowed (between 1045 hours and 1115 hours). Self-ratings of sleepiness/alertness (Karolinska Sleepiness Scale) were recorded every hour. At 10, 12, and 15 hours, the subjects performed a 28-minute visual vigilance task. Electroencephalograms (EEG) and electrooculograms (EOG) were recorded continuously, including during a 10-minute standardized recording procedure at the beginning of each day. Mean total sleep time during the nap was 19.8 (standard error 2.4) minutes.

Results: Compared to baseline, EEG/EOG sleepiness and subjective sleepiness were significantly higher and vigilance performance at 10 hours lower, respectively, after the two short sleeps.

Conclusions: The nap brought performance to baseline levels, and subjective sleepiness decreased significantly. It was concluded that the short nap had a clear positive effect on alertness.
4. The role of a short post-lunch nap in improving cognitive, motor, and sprint

WATERHOUSE J, ATKINSON G, EDWARDS B, REILLY T.
J Sports Sci 2007;25(14):1557-66.
Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, UK.


Overview: The aim of this study was to determine the effects of a post-lunch nap on subjective alertness and performance following partial sleep loss.

Protocol: Ten healthy males (mean age 23.3 years, s = 3.4) either napped or sat quietly from 13:00 to 13:30 h after a night of shortened sleep (sleep 23:00-03:00 h only). Thirty minutes after the afternoon nap or control (no-nap) condition, alertness, short-term memory, intra-aural temperature, heart rate, choice reaction time, grip strength, and times for 2-m and 20-m sprints were recorded.

Results:The afternoon nap lowered heart rate and intra-aural temperature. Alertness, sleepiness, short-term memory, and accuracy at the 8-choice reaction time test were improved by napping (P < 0.05), but mean reaction times and grip strength were not affected (P > 0.05). Sprint times were improved. Mean time for the 2-m sprints fell from 1.060 s (s(x) = 0.018) to 1.019 s (s(x) = 0.019) (P = 0.031 paired t-test); mean time for the 20-m sprints fell from 3.971 s (s(x) = 0.054) to 3.878 s (s(x) = 0.047) (P = 0.013). These results indicate that a post-lunch nap improves alertness and aspects of mental and physical performance following partial sleep loss, and have implications for athletes with restricted sleep during training or before competition.

5. The use of prophylactic naps and caffeine to maintain performance during a continuous operation.
BONNET MH, ARAND DL.
Ergonomics 1994;37(6):1009-20.
Dayton VA Hospital, Wright State University, OH 45428.


Protocol: After a normal baseline night of sleep and a morning of baseline test performance, 24 young adult male subjects returned to bed from 16:00-20:00 prior to a 24 h period of sleep loss. Twelve subjects received caffeine 200 mg at 01:30 and 07:30.

Results: Performance tests (correctly completed addition problems, vigilance sensitivity, and logical reasoning correct responses) all indicated maintenance of baseline performance levels in the caffeine group after administration of caffeine while performance declined in the placebo group. Similar results were found for the Multiple Sleep Latency Test and Oral Temperature, which both remained near baseline levels throughout the observation period in subjects receiving caffeine.

Conclusions: The results indicated that the combination of a prophylactic nap and caffeine was more effective in maintaining nocturnal alertness and performance than was the nap alone. Of more interest was the fact that the group which was given the combination of nap and caffeine was able to maintain alertness and performance at very close to baseline levels throughout a 24 h period without sleep.
6. Short nap versus short rest: recuperative effects during VDT work.
HAYASHI M, CHIKAZAWA Y, HORI T.
Ergonomics 2004;47(14):1549-60. Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-hiroshima, Japan.


Study: The effects of a 20-min nap during 2 h of visual display terminal (VDT) work were examined.

Methods: Ten young healthy adults took a 20-min nap or a 20-min rest I h after VDT work, followed by another 1 h of VDT work.

Results: A 20-min rest temporarily restored subjective sleepiness, but it deteriorated during the additional 1 h of work. In contrast, a 20-min nap maintained subjective alertness and performance level at a higher level and mental fatigue at a lower level for the additional 1 h of work.

Conclusions: These results suggest that a short nap would be useful to both fatigue recovery and fatigue prevention during continuous VDT work. The present findings may provide a new work/rest strategy.
7. Habitual napping moderates motor performance improvements following a short daytime nap.
MILNER CE, FOGEL SM, COTE KA.
Biol Psychol 2006 Mar 13
Brock University, Sleep Research Laboratory, St. Catharines, Ont., Canada


Study:The effect of napping on motor performance was examined in habitual and non-habitual nappers who were randomly assigned to a nap or reading condition. Motor procedural learning and auditory discrimination tasks were administered pre- and post-condition.

Results: Both groups reported improved alertness post-nap, but not post-reading. Non-habitual nappers fell asleep faster and tended to have greater sleep efficiency, but did not differ from habitual nappers on other sleep architecture variables. Habitual nappers had greater alpha and theta EEG power in stage 1, and greater delta, alpha and sigma power in stage 2 sleep. Motor performance deteriorated for non-habitual nappers who napped, but improved for all others. The number of sleep spindles and sigma power (13.5-15Hz) significantly predicted motor performance following the nap, for habitual nappers only.

Conclusions: Results indicate that motor learning was consolidated in a brief nap and was associated with stage 2 spindles, but only for those who habitually take naps.